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Oligonucleotides are used in numerous scientific applications, from biomedical research to drug development. In all of them, for oligonucleotides to be effective, it is essential that they are free of impurities. The purification of oligonucleotides is therefore a critical step in their manufacture. It is what is known as the downstream process within the production […]
Author Archives: oligofastx
05
Jul
Jul
Sol Spiegelman was a leading American molecular biologist whose work revolutionised our understanding of nucleic acids and their replication. Born in 1914, Spiegelman devoted his career to exploring the mechanisms of genetics and molecular biology, conducting groundbreaking research that has left a lasting impact on the field. His ability to combine theory with practical experiments […]
28
Jun
Jun
In recent years, the field of biomedicine has witnessed groundbreaking advances in the development of innovative therapies for a wide range of diseases Among these innovations, the development of oligonucleotide therapies has experienced a great development and in particular the field of antisense therapies with paradigmatic examples such as the approval of several drugs against […]
21
Jun
Jun
In medical research, there are several types of clinical trials that are designed according to the objective of the study and the nature of the treatment to be evaluated. On the other hand, clinical trials are fundamental to precision medicine, as they allow the efficacy and safety of personalised treatments to be rigorously and systematically […]
14
Jun
Jun
International Biotechnology Day is an opportunity to delve into the incredible advances and potential of this discipline. Biotechnology is the use of living organisms or parts of organisms for human benefit. Although we often think of it as a modern discipline, biotechnology has been part of our history since time immemorial. Early examples of biotechnology […]
16
May
May
Numerous types of oligonucleotides are synthesised every year for a wide variety of applications in laboratories and hospitals around the world. However, to fully understand this process, it is crucial to explore the origins of oligonucleotide synthesis and its connection to the evolution of modern biotechnology. The field of biotechnology has been shaped by a […]
03
May
May
Molecular biology has revolutionised our understanding of life and opened up a world of possibilities in scientific research and medical diagnosis. One of the most widely used techniques in this field is quantitative real-time PCR (qPCR), which combines the accuracy of DNA amplification with the ability to quantify the results in real time. The possibilities […]
25
Apr
Apr
At OLIGOFASTX, we are dedicated to the development and research of therapeutic oligonucleotides for rare diseases seeking advances in personalised medicine, where each patient can receive treatments specifically designed for their unique genetic needs. Therefore, we strongly believe in the power of multidisciplinary research profiles to drive the development of personalised therapies by combining expertise […]
10
Apr
Apr
At OLIGOFASTX, we work to develop therapeutic solutions for patients living with rare diseases. That is why World Health Day, celebrated every 7 April, is an occasion to reflect on the challenges and successes in global health. This year’s theme is “My Health, My Right”, highlighting the fundamental importance of equitable access to health services […]
01
Apr
Apr
In this eighth and final instalment of our #DiscoveringOligonucleotides series, we delve into the process of approval, registration and commercialisation of therapeutic oligonucleotides. Approval and registration The approval and registration process for therapeutic oligonucleotides, as for any other drug, is a critical step in their journey from the laboratory to the patient. This process involves […]