Category Archives: Technology

RNA therapies and their transformative impact on precision medicine

In this second issue of #DiscoveringOligonucleotides, from the OLIGOFASTX consortium we want to introduce you to RNA therapeutics. In the field of medicine, RNA therapies stand as pioneers, offering new approaches and promising advances in the treatment of diseases hitherto thought unattainable. RNA therapies operate at the most fundamental level of genetic information, using different […]

Challenges and ethics in the integration of Artificial Intelligence in the pharmaceutical industry

At the intersection of technological innovation and healthcare, artificial intelligence (AI) is emerging as a transformative tool in the pharmaceutical industry. This pairing promises to accelerate the discovery of new medicines, optimise production processes and improve patient care. However, with the promise comes a number of challenges and ethical conflicts that must be carefully addressed […]

Introduction to Therapeutic Oligonucleotides: Transforming Medicine from Genetics

Therapeutic oligonucleotides have emerged as an exciting and promising class of drugs capable of offering treatments for genetic and/or rare diseases. These DNA or RNA fragments have revolutionised the field of modern medicine… In this blog, we will explore what therapeutic oligonucleotides are, how they work and their potential applications, with a special focus on […]

The transformation of drug delivery in modern medicine

From the 1980s and 1990s to the present day, the field of drug delivery has undergone an extraordinary transformation that has redefined the way we administer medical treatments. This time period has seen revolutionary advances in drug delivery, driven by the convergence of nanotechnology, gene therapy and the search for more precise and effective treatments. […]

Larry Gold and Craig Tuerk: Pioneers in the Discovery of Aptamers

Advances in science and technology are often the result of the dedication, passion and collaboration of brilliant minds. One such remarkable breakthrough in the field of biotechnology is the discovery of aptamers, a class of molecules that has revolutionized research and diagnostics in biology and medicine. Larry Gold and Craig Tuerk are two names that […]

David Bartel and microRNAs

David Bartel (Birmingham, 1958) is a leading researcher in molecular and cell biology who has made significant contributions to the field of microRNAs. His work has been instrumental in understanding the biology of miRNAs and their importance in gene regulation. Bartel is known for his work in identifying miRNAs and elucidating their role in inhibiting […]

The evolution of knowledge about RNA: from its discovery to the present day

RNA is an essential molecule for life, but its discovery and understanding has been a decades-long process. In this article, we will explore the evolution of knowledge about RNA from its discovery to the present day and how it has revolutionised our understanding of molecular biology and genetics. Introduction: What is RNA? Ribonucleic acid (RNA) […]

RNA Bibliography: a selection of the most influential publications in the field of biotechnology

RNA Bibliography: a selection of the most influential publications in the field of biotechnology In the field of biotechnology, RNA research is revolutionising the biomedical sector. From OLIGOFASTX we share an essential scientific bibliographic selection because the knowledge embodied in the publications is a reference for professionals. There is much more, but the selection of […]

Enzymes: key molecules for the development of oligonucleotides

The OLIGOFASTX team is focused on the development of oligonucleotide-based therapies for certain rare diseases covering the whole cycle: from research to manufacturing and distribution of future new oligonucleotide-based drugs. To this end, the companies that make up the consortium are specialised in one area, which in combination provides a form of collaboration that allows […]