Category Archives: History of biotechnology

The legacy of Jacob and Monod: the molecular biology revolution

François Jacob and Jacques Monod transformed our understanding of genetics and laid the foundations of modern biology. Their work in the field of messenger RNA (mRNA, ( mRNA ) not only unravelled the mysteries of gene expression, it also not only unlocked the mysteries of gene expression, but also contributed to the explanation of how […]

Spiegelman’s Monster: a milestone in molecular biology

Sol Spiegelman was a leading American molecular biologist whose work revolutionised our understanding of nucleic acids and their replication. Born in 1914, Spiegelman devoted his career to exploring the mechanisms of genetics and molecular biology, conducting groundbreaking research that has left a lasting impact on the field. His ability to combine theory with practical experiments […]

Getting to know real-time quantitative PCR (qPCR)

Molecular biology has revolutionised our understanding of life and opened up a world of possibilities in scientific research and medical diagnosis. One of the most widely used techniques in this field is quantitative real-time PCR (qPCR), which combines the accuracy of DNA amplification with the ability to quantify the results in real time. The possibilities […]

Fire and Mello’s discovery of siRNAs: master keys to fighting disease

Small interfering RNA molecules (commonly known by the acronym siRNA small interfering RNA) represent one of the most revolutionary innovations in molecular biology and precision medicine. Their discovery, by scientists Andrew Fire and Craig Mello, was a milestone in biological research and was awarded the Nobel Prize in Physiology or Medicine in 2006. History of […]

Larry Gold and Craig Tuerk: Pioneers in the Discovery of Aptamers

Advances in science and technology are often the result of the dedication, passion and collaboration of brilliant minds. One such remarkable breakthrough in the field of biotechnology is the discovery of aptamers, a class of molecules that has revolutionized research and diagnostics in biology and medicine. Larry Gold and Craig Tuerk are two names that […]

David Bartel and microRNAs

David Bartel (Birmingham, 1958) is a leading researcher in molecular and cell biology who has made significant contributions to the field of microRNAs. His work has been instrumental in understanding the biology of miRNAs and their importance in gene regulation. Bartel is known for his work in identifying miRNAs and elucidating their role in inhibiting […]

The experiment that helped crack the code of life

In 1961, Marshall Nirenberg and Heinrich Matthaei discovered the genetic code of living beings, which confirms that the information contained in DNA is expressed in proteins according to a defined pattern. These researchers at the U.S. National Institutes of Health (NIH) made one of the scientific milestones that changed our view of how life develops […]

Tribute to Severo Ochoa, the Spanish biochemist who received the Nobel Prize for discovering the enzymes involved in RNA synthesis.

Of Spanish origin, the small and idyllic town of Luarca (Asturias) was the birthplace of one of the most influential and decisive figures in the history of biochemistry: Severo Ochoa de Albornoz. He was born on September 24, 1905, and died on November 1, 1993, but not before having traveled a crucial and key path […]