Author Archives: oligofastx

Cancer cachexia

Cancer cachexia is a complex metabolic syndrome characterized by marked loss of body weight, anorexia, asthenia, sarcopenia, and anemia. It is the most common manifestation of advanced malignant cancer, leading to death. Approximately half of all cancer patients experience cachexia and the prevalence is over 80% in terminally ill patients, with cachexia being responsible for […]

Providing solutions for rare diseases: a priority for the UN

Perhaps the definition is not the most accurate, but in reality a rare disease does nothing more than denominate a pathology that has not yet been studied, analyzed and against which there is, for the time being, no solution. The complexity of the processes to reach social development solutions for the improvement of patients’ quality […]

Innovative and sustainable production of biological molecules

The Oligofastx project covers all areas, from start to finish, of the process of developing oligonucleotides to fight several specific diseases: from design and preclinical research to production. Therefore, in this consortium, all the partners contribute their experience and knowledge in specific areas of action, thus completing a clear, consistent, coherent and results-oriented strategy. All […]

Personalized treatments for rare diseases with oligonucleotides pose universal challenges

There is no doubt that oligonucleotide therapies aimed at providing answers and improving the quality of life of patients with certain rare diseases, which still have no solution, are a hopeful prospect. The path, already started with numerous initiatives, Oligofastx among them, is also a reality. But much research remains to be done, not only […]

Oligonucleotides, the language of life in small doses

A technological revolution can start with a key concept, the application of an equation or, often, with the development of a particular material. Steels, alloys, concretes, liquid fuels, semiconductors or polymers are examples that changed the history of mankind and today are ubiquitous in our lives. The pharmaceutical industry is no different. Thus, the ability […]